September 2021: Michelle, Wei Heng, Wei Kee, and Howard join our lab to pursue research under the URECA programme for outstanding undergraduate students. Welcome!
August 2021: Yi Yong, Cheryl, Shannon, and Zheng Qiao join our lab for their FYP. Welcome!
July 2021: Our PhD student, Joel, passes his qualifying exam. Congratulations!
April 2021: Our undergraduate students are taking part in the iGEM synthetic biology competition this year. Good luck!
March 2021: Our CRISPR diagnostic assay for COVID-19, named VaNGuard, has been published in Nature Communications. Congratulations to the team!
The DaRE Lab is interested in DNA and RNA editing, particularly in the context of cell identity. Although living cells have biological information hardwired into their genomes, this information can be naturally or artificially altered, either at the level of DNA where the changes can be permanent or at the level of RNA where the changes can be dynamic. We are focused on (1) developing and applying powerful new genome engineering technologies to understand cell fate decisions and (2) unraveling the functions and regulation of RNA editing in human development and diseases. Our research activities fall under the broad umbrella of systems and synthetic biology.