November 2016: Assistant Professor Tan presented a seminar at the Division of Biomedical Engineering in Hong Kong University of Science and Technology on our laboratory's research on RNA editing. It was a great networking session with the faculty and students at HKUST!
November 2016: Assistant Professor Tan gave a talk at the Cell Symposium on Functional RNAs on our laboratory's research on the regulation of RNA editing. We received positive feedback about our work!
October 2016: The NTU iGEM team led by Assistant Professor Tan was awarded a Gold medal for their research on CRISPR-Cas. The team was also awarded the prize for the Best Measurement Project as well as the prize for the Best Wiki (Overgrad). Additionally, they were nominated for the Best Basic Part prize and were commended during the Giant Jamboree for performing research that has high society impact. Congratulations to the team!
September 2016: Kelvin, Ignatius, Jaclyn, Hsin-Yueh, Danny, and Kar Ming join our lab to pursue research under the URECA programme for outstanding undergraduate students. Welcome!
August 2016: Shi Mun Lee and Fei Wang join our lab to pursue their masters degrees in biomedical engineering. Welcome!
July 2016: Our work on engineering a fast chemical-inducible CRISPR-Cas9 system has been accepted by Nature Chemical Biology! Congratulations to Ivy Liu and the rest of the team!
February 2016: Dr. Jia Li joins our lab from the Chinese Academy of Sciences. Welcome!
January 2016: Dr. Yuanming Wang joins our lab from Shanghai Jiao Tong University. Welcome!
The DaRE Lab is interested in DNA and RNA editing, particularly in the context of cell identity. Although living cells have biological information hardwired into their genomes, this information can be naturally or artificially altered, either at the level of DNA where the changes can be permanent or at the level of RNA where the changes can be dynamic. We are focused on (1) developing and applying powerful new genome engineering technologies to understand cell fate decisions and (2) unraveling the functions and regulation of RNA editing in human development and diseases. Our research activities fall under the broad umbrella of systems and synthetic biology.