DNA and RNA  Editing (DaRE) Lab

​17. Tan M.H.*†, Q. Li*, R. Shanmugam, R. Piskol, J. Kohler, A.N. Young, K.I. Liu, R. Zhang, G. Ramaswami, K. Ariyoshi, A. Gupte, L.P. Keegan, C.X. George, A. Ramu, N. Huang, E.A. Pollina, D. Leeman, A. Rustighi, Y.P.S. Goh, The GTEx Consortium, A. Chawla, G. Del Sal, G. Peltz, A. Brunet, D.F. Conrad, C.E. Samuel, M.A. O’Connell, C.R. Walkley, K. Nishikura, and J.B. Li†. 2017. Dynamic landscape and regulation of RNA editing in mammals. Nature 550: 249-254.

16. Shi S., Y.W. Choi, H. Zhao, M.H. Tan, and E.L. Ang. 2017. Discovery and engineering of a 1-butanol biosensor in Saccharomyces cerevisiae. Bioresource Technology 245 (Part B): 1343-1351.

​15. Choi Y.J.*, C.P. Lin*, D. Risso*, S. Chen, T.A. Kim, M.H. Tan, J.B. Li, Y. Wu, C. Chen, Z. Xuan, T. MacFarlan, W. Peng, K.C. Lloyd, S.Y. Kim, T.P. Speed, and L. He. 2017. Deficiency of miRNA miR-34a expands cell fate potential of pluripotent stem cells. Science 355(6325): eaag1927.

​14. K.I. Liu, M.N.B. Ramli, C.W.A. Woo, Y. Wang, T. Zhao, X. Zhang, G.R.D. Yim, B.Y. Chong, A. Gowher, M.Z.H Chua, J. Jung, J.H.J. Lee, and M.H. Tan. 2016. A chemical-inducible CRISPR-Cas9 system for rapid control of genome editing. Nature Chemical Biology ​​12(11): 980-987. (Cover article)

13. Zheng M., H. Zhang, D.L. Dill, J.D. Clark, S. Tu, A.L. Yablonovitch, M.H. Tan, R. Zhang, D. Rujescu, M. Wu, L, Tessarollo, W. Vieira, M.M. Gottesman, S. Deng, L.S. Eberlin, R.N. Zare, J.-M. Billard, J.-P. Gillet, J.B. Li, and G. Peltz. 2015. The role of Abcb5 alleles in susceptibility to haloperidol-induced toxicity in mice and humans. PLoS Medicine 12(1): e1001782.

​12. Zheng Q.*, Cai X.*, M.H. Tan, S. Schaffert, C.P. Arnold, X. Gong, C.-Z. Chen, and S. Huang. 2014. Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells. BioTechniques 57(3): 115-124.

​11. Kukurba K.R., R. Zhang, X. Li, K.S. Smith, D.A. Knowles, M.H. Tan, R. Piskol, M. Lek, M. Snyder, D.G. MacArthur, J.B. Li, and S.B. Montgomery. 2014. Allelic expression of deleterious protein-coding variants across human tissues. PLoS Genetics 10(5): e1004304.

10. Tan M.H. and J.B. Li. 2013. Identification of RNA editing sites: a Survey of the Past, Present, and Future. In RNA Editing: Current Research and Future Trends (editor S. Maas). Horizon Press: Norwich.

9. Tan M.H.*, K.F. Au*, D.E. Leong, K. Foygel, W.H. Wong, and M.W.M. Yao. 2013. An Oct4-Sall4-Nanog network controls developmental progression in the pre-implantation mouse embryo. Molecular Systems Biology 9: 632.

8. Tan M.H.*†, K.F. Au*, A.L. Yablonovitch*, A.E. Wills, J. Chuang, J.C. Baker, W.H. Wong, and J.B. Li†. 2013. RNA sequencing reveals diverse and dynamic repertoire of the Xenopus tropicalis transcriptome over development. Genome Research 23: 201–216.

7. Ramaswami G.*, W. Lin*, R. Piskol*, M.H. Tan, C. Davis, and J.B. Li. 2012. Accurate identification of human Alu and non-Alu RNA editing sites. Nature Methods 9: 579-581.

6. Lin W.*, R. Piskol*, M.H. Tan, and J.B. Li. 2012. Comment on “Widespread RNA and DNA sequence differences in the human transcriptome”. Science 335(6074): 1302.

5. Tan M.H., J.B. Kozdon, X. Shen, L. Shapiro, and H.H. McAdams. 2010. An essential transcription factor, SciP, enhances robustness of Caulobacter cell cycle regulation. Proc. Natl. Acad. Sci. USA 107(44): 18985-18990.

4. Jedrusik A., A.W. Bruce*, M.H. Tan*, D.E. Leong, M. Skamagki, M. Yao, and M. Zernicka-Goetz. 2010. Maernally and zygotically provided Cdx2 have novel and critical roles for early development of the mouse embryo. Developmental Biology 344: 66-78.

3. McGrath P.T., H.Lee, L. Zhang, A.A. Iniesta, A.K. Hottes, M.H. Tan, N.J. Hillson, P. Hu, L. Shapiro, and H.H. McAdams. 2007. High-throughput identification of transcription start sites, conserved promoter motifs and predicted regulons. Nature Biotechnology 25(5): 584-592.

2. El-Naggar M.Y.*, J.T. Klamo*, M.H. Tan*, and H.G. Hornung. 2004. Experimental verification of the Mach-number field in a supersonic Ludwieg tube. AIAA Journal 42(8): 1721-1724.

1. O’Reilly O.M. and M.H. Tan. 2004. Steady motions of an axisymmetric satellite: An atlas of their bifurcations. International Journal of Nonlinear Mechanics 39(6): 921-940.

* Equal contributions
† Co-corresponding authors